Urticaria Pigmentosa Information and Treatment
Urticaria pigmentosa is a disease which forms skin lesions and intensive itching. If the lesions are rubbed, hives can develop on the site. Urticaria pigmentosa mainly affects infants, with the first patches appearing at a few months of age.Urticaria pigmentosa is an uncommon rash which commonly affects the neck, arms, legs and trunk of children and young adults. Urticaria pigmentosa is one of several forms of mastocytosis, which is caused by immoderate numbers of inflammatory cells (mast cells) in the skin. Urticaria pigmentosa is most often found in children, but it can occur in adults as well.
Urticaria pigmentosa is identified by several to many brownish spots that itch and, when scratched, make welts and reddened skin. Mastocytosis is a group of disorders in both children and adults caused by the occurrence of too many mast cells in a person's body.
Most usual type of mastocytosis, characterized by various persistant small reddish brown hyperpigmented pruritic macules and papules. Mast cells work by releasing chemicals which draws white blood cells to areas of the body where they are needed.
Researchers also suppose mast cells may have a role in the growth of blood vessels. The condition occurs chiefly in children and clears spontaneously with adolescence. Rubbing of a lesion makes a quick wheal (a hive-like bump). Younger children can form a fluid-filled blister over a lesion if it is scratched.
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